C-Flex® TPE Tubing
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C-Flex® TPE Tubing

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C-Flex® 374 is a patented, premium thermoplastic elastomer (TPE) tubing engineered for high-purity fluid transfer in pharmaceutical, biopharmaceutical, and life sciences applications. It is widely used in single-use assemblies, peristaltic pump operations, and aseptic welding and sealing processes. Manufactured under tightly controlled conditions, C-Flex® 374 offers excellent chemical resistance to acids, bases, salts, and high-purity water, along with significantly lower gas permeability compared to silicone. The tubing supports multiple sterilization methods, including gamma irradiation (up to 40 kGy) and autoclave (121°C for 30 minutes), and operates across a broad temperature range of -67°C to 135°C. Its clarity enables easy visual flow monitoring, and it meets global regulatory standards including USP Class VI and ISO 10993, while being entirely free of animal-derived components (ADCF), ensuring suitability for the most demanding bioprocess environments.
$29.46 $58.93you save $29.47
SKU: 374-125-2

Relevant Industries

• Strong Acid & Strong Base Solutions
• Aseptic Sealing Disconnections
• Aseptic Welding Connections
• Peristaltic Pumps
• Cell Culture Operations
• Tubing and Bag Manifolds
• Single-Use Fluid Transfer Sets
• Ideal For Use in Single-Use Assemblies
• Buffer and Media Preparation

Applications

• Strong Acid & Strong Base Solutions
• Aseptic Sealing Disconnections
• Aseptic Welding Connections
• Peristaltic Pumps
• Cell Culture Operations
• Tubing and Bag Manifolds
• Single-Use Fluid Transfer Sets
• Ideal For Use in Single-Use Assemblies
• Buffer and Media Preparation

• Sealable & weldable before or after sterilization; easily moldable and formable


• Low gas permeability, outperforming silicone in fluid and gas containment


• Sterilization-ready: autoclavable (one-time 121°C/30 min) and gamma compatible (up to 40 kGy)


• Exceptional chemical resistance to acids, bases, salts, and high-purity water


• Temperature range: -67°C to 135°C (-85°F to 275°F)


• Animal-derived component free; compliant with ISO, USP, and biocompatibility standards


• Physical Properties
o Durometer: Shore A 60 (ASTM D2240)
o Tensile Strength: 1190 psi | Elongation: 915% (ASTM D412)
o Brittle Point: -66°C (ASTM D746)
o Compression Set: 83% (ASTM D395)


• Available in multiple sizes with varying I.D., O.D., wall thickness, working pressures, and vacuum ratings

• Genotoxicity Test: Passed ISO 10993-3 standards.
• Hemolysis: For indirect contact, passed ISO 10993-4 standards.
• System Toxicity Testing: Rabbit Pyrogen: Meets ISO 10993-11 criteria.
• Biocompatibility: Passed USP <87> (in vitro) biological reactivity tests. Passed USP <88> Class VI (in vivo) biological reactivity tests.
• Endotoxin Testing: Passed USP <85> Limulus Amebocyte Lysate test.
• Sterility Test: Bacteriostasis & Fungistasis: Passed USP <71>
• Physicochemical Tests for Plastics: Passed USP <661>
• Rubber Closures for Containers: Meets EP 3.2.9 criteria
• Regulatory Compliance: All formulas are Animal-Derived Component Free. Validation Guide and Regulatory Information Overview (RIO) available upon request.

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