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Biological Grade – Multi Layer CRT-PP-M Series PP Media Filter Cartridge [Absolute]

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Elevate critical biological processes with the IFP CRT-PP-M Series Absolute Multilayer Filter Cartridge, a uniquely engineered solution by International Filter Products (IFP). This cartridge is strategically designed with multiple layers of polypropylene to achieve 99.98% absolute filtration efficiency, delivering exceptional performance for biological-grade applications, protein purification, and blood serum processing.

Unlike standard filters, this multilayer construction offers graduated micron filtration within a single cartridge—minimizing protein binding, preserving sensitive biomolecules, and enhancing process throughput. It is a reliable replacement for lenticular filters, cellulose sheets, and filter presses, dramatically reducing product loss and waste during clarification and sterile prefiltration stages.

Your selected cartridge includes pre-installed Silicone O-Rings. Upgrade options for O-Ring materials are available below:

Your selected cartridge includes pre-installed Viton O-Rings. Upgrade options for O-Ring materials are available below:

Your selected cartridge includes pre-installed Viton O-Rings. Upgrade options for O-Ring materials are available below:

Your selected cartridge includes pre-installed Buna-N O-Rings. Upgrade options for O-Ring materials are available below:

Your selected cartridge includes pre-installed Buna-N O-Rings. Upgrade options for O-Ring materials are available below:

$0.14
$0.23
$0.17
$1.58
$1.68
$0.14
$0.23
$0.17
$1.68
$1.58
$0.31
$0.05
$0.11
$1.87
$1.46
$0.14
$0.23
$0.17
$1.68
$1.58
$0.14
$0.23
$0.17
$1.68
$1.58
$0.14
$0.23
$0.17
$1.68
$1.58
$0.14
$0.23
$0.17
$1.68
$1.58
$0.14
$0.23
$0.17
$1.68
$1.58
$0.14
$0.23
$0.17
$1.58
$1.68
$0.14
$0.23
$0.17
$1.58
$1.68
$0.31
$0.31
$0.17
$1.87
$1.46
$0.14
$0.23
$0.17
$1.68
$1.58
$0.31
$0.31
$0.17
$1.87
$1.46
$0.14
$0.23
$0.17
$1.58
$1.68
$0.14
$0.23
$0.17
$1.58
$1.68
$0.14
$0.23
$0.17
$1.58
$1.68
$0.31
$0.31
$0.05
$1.87
$1.46
$0.14
$0.23
$0.17
$1.68
$1.58
$0.14
$0.23
$0.17
$1.68
$1.58
$0.14
$0.23
$0.17
$1.58
$1.68
$0.14
$0.23
$0.17
$1.58
$1.68
Not Seeing Your Configuration? Contact IFP for a tailored cartridge solution.
SKU: CRTPP10M010006002A7S

Relevant Industries

• Biological Pharmaceuticals

• Biotechnology & Life Sciences

• Blood Serum Processing

• Veterinary Biologics

Ideal for fine particle retention and sterilization filtration in:
• Blood Serum Clarification
• Protein Engineering & Peptide Filtration
• Cell Culture Media Filtration
• Biologics Pre-Filtration
• Vaccine and Antibody Processing
• Fermentation Broth Clarification
• Upstream Process Protection (pre-sterile filtration)

• Popular Micron Rating Combinations (Multilayer Configurations):
1. Triple Layer 10.0 μm / 3.0 μm / 0.45 μm
2. Triple Layer 10.0 μm / 5.0 μm / 1.0 μm
3. Triple Layer 5.0 μm / 1.0 μm / 0.65 μm
4. Triple Layer 1.0 μm / 0.65 μm / 0.25 μm
5. Triple Layer 30.0 μm / 15.0 μm / 5 μm

• Effective Filtration Area:
1. 5-Inch: 3.75 ft² (0.35 m²)
2. 10-Inch: 7.5 ft² (0.7 m²)
3. 20-Inch: 15.0 ft² (1.4 m²)
4. 30-Inch: 22.5 ft² (2.1 m²)

• Typical Filtered Volume:
1. 5-Inch: 50L–250L
2. 10-Inch: 100L–500L
3. 20-Inch: 200L–1,000L
4. 30-Inch: 300L–1,500L

• Materials of Construction:
1. Filter Media: Multilayer Polypropylene
2. Supports, Core, Cage, End Caps: Polypropylene
3. O-Rings: Silicone (Standard), EPDM, Viton, or Teflon-encapsulated options
4. Sealing: Thermally bonded, adhesive-free


• Operating Conditions:
1. Max Forward Differential Pressure: 5.5 bar (80 psi) at 25°C
2. Max Operating Temp: 80°C (176°F) at 0.7 bar
3. Min Burst Pressure: 8.3 bar (120 psi)
4. Max Reverse Pressure: 3.0 bar (44 psi)

• Filtration Efficiency:
1. Absolute Rated: ≥99.98% removal efficiency


• Biocompatibility & Compliance:
1. USP <87>: In Vitro Cytotoxicity
2. USP <88>: In Vivo Reactivity (Class VI Plastics)
3. ASTM F756-17: Hemolysis Testing
4. FDA 21 CFR 177: Indirect Food Additive Compliance
5. No animal-derived materials used in manufacturing


• Sterilization Compatibility:
1. Autoclave: Up to 50 cycles at 125°C for 30 min
2. Steam-in-Place (SIP): Up to 30 cycles at 135°C for 30 min
3. Hot water or chemical sanitization options available


• Traceability:
1. Certificate of Conformance with each cartridge
2. Laser-engraved part number and lot number on each filter
3. Fully labeled bag and box for supply chain traceability


• Cleanliness:
1. Rinsed with pharmaceutical-grade 17+ MΩ purified water


• Shelf Life:
1. 3 years from the date of manufacture

Fit of IFP CRT Cartridges with Filter Housings

The choice of cartridge end cap significantly impacts sealing performance, pressure rating, and fluid distribution. The 226 O-Ring Fin (Code 7) is the most secure and widely used in critical applications, while DOE (Code 0) remains an older technology; its use is limited mainly to non-sterile processes.

End Cap Type Housing Connection Details
226 O-Ring Fin (Code 7) Most Popular - Highest Pressure Rating Recessed 226 O-ring groove with locking tabs and center receptor for fin Offers the most secure fit with dual O-ring compression and bayonet locking tabs. The integrated fin aligns the cartridge, enhancing pressure stability and promoting even solution distribution.
222 O-Ring Flat (Code 2) Recessed 222 O-ring groove with flat bottom The housing head features a precision-machined cavity to fit the 222 O-ring, ensuring tight axial compression. Uses a flat receptacle-no locking tabs.
226 O-Ring Flat (Code 6) Recessed 226 O-ring groove with flat bottom Features a wider, deeper groove for 226 O-rings. Provides enhanced sealing over 222 but lacks bayonet lock or fin alignment.
Flat Gasket (Code 0) Least Popular - Lowest Pressure Rating Flat knife-edge or gasket seat at both ends Cartridge is held by compression plates or spring caps. No O-rings or locking tabs-best for low-pressure, general-purpose filtration.

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